Senior Medical Program Manager (MPM) – One Medical Early Assets

Job title:  Senior Medical Program Manager (MPM) – One Medical Early Assets

Location: Cambridge, MA

About the Job

The MPM will provide program management expertise, team and portfolio management, and strategic operational support across the One Medical early asset portfolio, enabling integrated medical inclusion from discovery through proof of concept. This individual will work closely with the Medical Program Lead (MPL), Early Asset Global Medical Leads (GMLs), and Global Medical Teams (GMTs), both internally and with alliance partners where applicable, to ensure medical knowledge and insights flow seamlessly across the early-development value chain, forging aligned partnerships across R&D. The position sits within the NextGen Immunology (NGI) team but carries responsibility across One Medical SPC and Gen Meds. Working in a matrix environment, the MPM drives strategic direction and operational execution, ensuring teams are empowered to innovate boldly together across the early medical lifecycle.

Join the engine of Sanofi’s mission — where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive breakthroughs that could turn the impossible into possible for millions.

About Sanofi

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Main Responsibilities

Provide program management expertise, team and portfolio management, and strategic operational support across the One Medical early asset portfolio

Enable integrated medical inclusion across early-stage assets from discovery through proof of concept

Drive strategic direction and operational execution, ensuring the GML has line of sight across R&D to deliver impact in the Global Project Teams (GPTs) from M2

Position Medical to co-lead Disease Area Strategies in partnership with R&D

Forge strategic partnerships and shared governance with the TMU ECET Program, CSU eProtocol, and Patient Driven Medicine Development

Plan, Coordinate and Co-partner on driving the early iEGP (Integrated Evidence Generation Plan) roadmap at both disease area and asset level

Drive evidence generation prioritization in partnership with the GML

Design, coordinate, and co-lead a Global Medical Team (GMT) system that ensures resource efficiency and a strong matrixed network across global medical, local medical, and cross-functional partners early in the medical lifecycle

Establish a framework for operationalizing medical strategy, tactics, and clinical investment planning for early medical and budget needs as assets advance through the lifecycle, for use by asset and disease area teams

Manage portfolio and operational level activities via the harmonized Program Management Tool used across the MPM organization

Ensure workflows and processes are efficient and compliant with internal SOPs and external guidelines

About You

Basic requirements:

Bachelor's degree in Life Sciences, Biomedical Sciences, Pharmacy, Health Sciences, or a related scientific discipline required. Advanced scientific degree (MS, PharmD, PhD, MD) preferred; MBA or equivalent business qualification is a plus.

Minimum 5 years of project/program management, portfolio management, or related experience within the biopharmaceutical, biotechnology, healthcare, clinical research, or scientific environment, with experience supporting cross-functional teams and complex initiatives.

Background in the biopharmaceutical or pharmaceutical industry with direct experience in project/program management; scientific background and Medical Affairs experience preferred.

Ability to lead projects and translate strategy into tactical plans and reusable frameworks

Thorough understanding of project/program management techniques and methodology

Ability to foster teamwork and collaboration coordinating cross-functional teams in a matrix environment

Ability to manage projects end to end with minimum supervision

Ability to establish and provide frequent reporting dashboards with key metrics utilizing harmonized methodologies

Strong interpersonal and communication skills with the ability to effectively interface across all levels of the organization

Ability to multitask and maintain tight timelines and priorities in a highly professional manner

Excellent knowledge of MS Office; working knowledge of program/project management software

Why Choose Us? 

Bring the miracles of science to life alongside a supportive, future-focused team.

Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.

Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.

Help improve the lives of millions of people globally by making drug development quicker and more effective.

Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.